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Titlebook: Stem Cells and Cardiac Regeneration; Rosalinda Madonna Book 2016 Springer International Publishing Switzerland 2016 cardiomyocyte.microRNA

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发表于 2025-3-21 17:25:50 | 显示全部楼层 |阅读模式
书目名称Stem Cells and Cardiac Regeneration
编辑Rosalinda Madonna
视频videohttp://file.papertrans.cn/878/877268/877268.mp4
概述Covers current understanding/challenges in basic/translational aspects of cell therapy for cardiac disorders in a rational and stepwise manner.Provides the basis of how a concept in cardiac cell thera
丛书名称Stem Cell Biology and Regenerative Medicine
图书封面Titlebook: Stem Cells and Cardiac Regeneration;  Rosalinda Madonna Book 2016 Springer International Publishing Switzerland 2016 cardiomyocyte.microRNA
描述.This book provides an update of recent advances in the basic and clinical applications of cell-based therapies for myocardial repair and regeneration in ischemic heart disease (IHD) and heart failure (HF). The first sections of the book illuminate basic aspects of stem cells such as definitions, isolation criteria and characterization of embryonic and adult stem cells, as well as pluripotent stem cells and tissue specific progenitor and stem cells. In the following section, the text examines the role of critical regulators of stem cell differentiation in myocardial regeneration, that include circadian rhythyms, microRNAs, epigenetics, microvescicles, and exosomes. The text concludes with a review of the use of stem/progenitor cells in cardiac regeneration and discuss current controversies, unresolved issues, challenges, and future directions. .Stem Cells and Cardiac Regeneration .is addressed to a wide audience consisting of cardiologists, clinicians, and research scientists, who will learn new concepts in cardiovascular regeneration and repair with special focus on molecular mechanisms and therapeutic potential for cardiovascular regeneration. .
出版日期Book 2016
关键词cardiomyocyte; microRNAs; myocardial regeneration; pluripotent stem cells; Epigenetics
版次1
doihttps://doi.org/10.1007/978-3-319-25427-2
isbn_softcover978-3-319-79786-1
isbn_ebook978-3-319-25427-2Series ISSN 2196-8985 Series E-ISSN 2196-8993
issn_series 2196-8985
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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发表于 2025-3-22 00:19:00 | 显示全部楼层
Microvesicles and Exosomes in Local and Distant Communication with the Hearting to their isolation and characterization remain to be overcome, and many aspects of their processing in vivo remain hypothetical. This chapter will examine the evidence for a role of exosome and microvesicles in local and distant communication mechanisms in the heart, particular in ischaemic heart failure and after myocardial infarction.
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Tissue Specific Progenitors/Stem Cells for Cardiac Regeneration progenitor cells and bone marrow-derived stromal stem cells. Long-term studies with bone marrow-derived cells have however shown that new myocytes do not acquire the adult phenotype. Furthermore, the bone marrow is not easily accessible, and harvesting of bone marrow determines discomfort to the pa
发表于 2025-3-22 19:25:52 | 显示全部楼层
Circadian Rhythms in Stem Cell Biology and Functiona central clock in the suprachiasmatic nucleus (SCN) within the brain, and peripheral clocks in multiple other tissues. While the central clock is entrained by light, peripheral clocks are kept in synchrony by the SCN via humoral factors, metabolites and body temperature. Additionally, SCN independe
发表于 2025-3-22 23:27:10 | 显示全部楼层
Cardiac Regeneration and microRNAs: Regulators of Pluripotency, Reprogramming, and Cardiovascular Lif mRNA decay. One miRNA can potentially target up to several hundred mRNAs, which makes miRNAs powerful regulators of gene expression patterns rather than single genes. miRNAs are involved in almost every biological process, including self-renewal, pluripotency, reprogramming, and differentiation, a
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Stem Cell Secretome and Paracrine Activityherapeutic approaches to minimize, prevent, or reverse cardiac damage. In recent years stem cell-based approaches have gained considerable attention from scientists as well as the public. A publication by Orlic and coworkers describing that “locally delivered bone marrow cells can generate de novo m
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