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Titlebook: Stem Cells and Cancer; Sadhan Majumder Book 2009 Springer-Verlag New York 2009 cancer.cancer research.cancer therapy.molecular mechanisms.

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书目名称Stem Cells and Cancer
编辑Sadhan Majumder
视频video
概述Will provide timely, cutting-edge information about cancer stem cells from the perspectives of both the basic and clinical sciences
图书封面Titlebook: Stem Cells and Cancer;  Sadhan Majumder Book 2009 Springer-Verlag New York 2009 cancer.cancer research.cancer therapy.molecular mechanisms.
描述.Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (which are typically aberrant compared with mechanisms in normal tissue), and the lack of good mechanism-based therapeutic approaches. The recent findings that most cancers contain a small fraction of self-renewing, differentiation-blocked stem cell-like cells (cancer stem cells) and that it is these cells—and not the major bulk of the tissue—that are the root cause for cancer initiation and metastasis have also highlighted the need to change our approach to cancer therapy...The objectives of this book, therefore, would be to impart up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies..
出版日期Book 2009
关键词cancer; cancer research; cancer therapy; molecular mechanisms; regulation; stem cell cancer research; stem
版次1
doihttps://doi.org/10.1007/978-0-387-89611-3
isbn_softcover978-1-4899-8287-2
isbn_ebook978-0-387-89611-3
copyrightSpringer-Verlag New York 2009
The information of publication is updating

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Cancer Stem Cells and Metastasis: Emerging Themes and Therapeutic Implications,ors. Insights into intrinsic properties of cancer stem cells are especially important in the context of tumor invasion and metastasis. Although more research is still necessary to solidify the role of cancer stem cells in the initiation of metastatic growth, the multistep cascade of tumor growth and
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Stem Cells and Lung Cancer,ances in current treatment modalities, overall survival rates have hardly improved. Overall 5-year lung cancer survival rate is approximately 15% in the USA and these numbers are much lower in the developing world. The intrinsic resistance shown by stem/progenitor cells following traditional chemoth
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