Titlebook: Stem Cells; Therapeutic Applicat Mariusz Z. Ratajczak Book 2019 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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Stefania Bruno,Sharad Kholia,Maria Chiara Deregibus,Giovanni Camussi

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Genomic Instability of iPSCs and Challenges in Their Clinical Applications, variations to point mutations. On the basis of their origin, these genetic aberrations in iPSCs can be classified as (i) preexisting mutations in parental somatic cells, (ii) reprogramming-induced mutations, and (iii) mutations that arise during in vitro culture. However, it is still unknown whethe

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,Stem Cells in the Mammalian Gonads,ed to regenerate nonfunctional gonads of cancer survivors, and thus there is possibly no need to bank testicular/ovarian tissue prior to oncotherapy. Being developmentally linked to the primordial germ cells (PGCs) which are the natural precursors to the gametes, VSELs differentiate into haploid spe

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,Stem and Progenitor Cells in the Pathogenesis and Treatment of Digestive Diseases, various stem and progenitor cells of adult tissues circulating in peripheral blood and their role in the pathogenesis and treatment of digestive diseases. We also briefly discuss the role of host-stem cell-microbial interactions as a new frontier of research in gastroenterology.

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