Titlebook: Stem Cell Microenvironments and Beyond; Alexander Birbrair Book 2017 Springer International Publishing AG 2017 dental pulp cells.hematopoi

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Book 2017ion, as well as modern methodologies and new techniques for the identification and characterization of stem cell niches, are discussed by leading experts in the field. Chapters describe the major components of various stem cell microenvironments, such as cellular components, soluble factors, cell-ce

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Leukemia Stem Cells Microenvironment,rties including localization, self-renewal, differentiation, and proliferation. Recent research of normal and leukemia BM microenvironments has revealed several key components of specific niches that provide a sanctuary where subpopulations of leukemia cells evade chemotherapy-induced death and acqu

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Developmental HSC Microenvironments: Lessons from Zebrafish,ted by its microenvironment. During development, HSCs acquire the instructions to self-renew and differentiate into all blood cell fates by passing through several developmental microenvironments. In this chapter, we discuss the signals and cell types that inform HSC decisions throughout ontogeny wi

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Glioblastoma Stem Cells and Their Microenvironment,ur due to progression of slower growing grade III astrocytomas. GBM is characterized by extensive hypoxia, angiogenesis, proliferation and invasion. Standard treatment options such as surgical resection, radiation therapy and chemotherapy have increased median patient survival to 14.6 months in adul