书目名称 | Stem Cell Genetics for Biomedical Research | 副标题 | Past, Present, and F | 编辑 | Raul Delgado-Morales | 视频video | | 概述 | This volume presents an up-to-date compendium of major scientific breakthroughs on human diseases, drug screenings, personalized medicine and regenerative approaches by using stem cells to model or tr | 图书封面 |  | 描述 | .This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. .In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be r | 出版日期 | Book 2018 | 关键词 | disease modeling; cell transplantation; somatic; brain disorders; cardiovascular; therapeutics | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-90695-9 | isbn_softcover | 978-3-030-08076-1 | isbn_ebook | 978-3-319-90695-9 | copyright | Springer International Publishing AG, part of Springer Nature 2018 |
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