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Titlebook: Statistics in Clinical and Observational Vaccine Studies; Jozef Nauta Book 2020Latest edition Springer Nature Switzerland AG 2020 Vaccine

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发表于 2025-3-21 19:21:21 | 显示全部楼层 |阅读模式
书目名称Statistics in Clinical and Observational Vaccine Studies
编辑Jozef Nauta
视频video
概述Offers a comprehensive guide to the current state of statistical methods for clinical vaccine trials.Shares key insights into the analysis of vaccine field studies, including observational ones.Featur
丛书名称Springer Series in Pharmaceutical Statistics
图书封面Titlebook: Statistics in Clinical and Observational Vaccine Studies;  Jozef Nauta Book 2020Latest edition Springer Nature Switzerland AG 2020 Vaccine
描述.This book offers an overview of the statistical methods used in clinical and observational vaccine studies. Pursuing a practical rather than theoretical approach, it presents a range of real-world examples with SAS codes, making the application of the methods straightforward. ..This revised edition has been significantly expanded to reflect the current interest in this area. It opens with two introductory chapters on the immunology of vaccines to provide readers with the necessary background knowledge. It then continues with an in-depth exploration of the analysis of immunogenicity data. Discussed are, amongst others, maximum likelihood estimation for censored antibody titers, ANCOVA for antibody values, analysis of data of equivalence, and non-inferiority immunogenicity studies. Other topics covered include fitting protection curves to data from vaccine efficacy studies, and the analysis of vaccine safety data...In addition, the book features four new chapters on vaccine field studies: an introductory one, one on randomized vaccine efficacy studies, one on observational vaccine effectiveness studies, and one on the meta-analysis of vaccine efficacy studies. ..The book offers usef
出版日期Book 2020Latest edition
关键词Vaccine Immunology; Statistical Analysis of Vaccine Trials Data; Vaccine Equivalence and Non-Inferiori
版次2
doihttps://doi.org/10.1007/978-3-030-37693-2
isbn_softcover978-3-030-37695-6
isbn_ebook978-3-030-37693-2Series ISSN 2366-8695 Series E-ISSN 2366-8709
issn_series 2366-8695
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

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Book 2020Latest editioncal approach, it presents a range of real-world examples with SAS codes, making the application of the methods straightforward. ..This revised edition has been significantly expanded to reflect the current interest in this area. It opens with two introductory chapters on the immunology of vaccines t
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Standard Statistical Methods for Immunogenicity Datald increase, the seroprotection rate and the seroconversion rate—are introduced. For each of these summary statistics, the standard statistical analysis is covered in great detail, both for single vaccine and comparative vaccine trials. A persistent misconception about the geometric mean fold increa
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