书目名称 | Statistical Monitoring of Clinical Trials | 副标题 | Fundamentals for Inv | 编辑 | Lemuel A. Moyé | 视频video | | 概述 | Presents the basics of monitoring procedures in clinical research with limited reliance on mathematics.Explores the background, correct use, and interpretation of these monitoring procedures at an ele | 图书封面 |  | 描述 | .Statistical Monitoring of Clinical Trials: Fundamentals for Investigators introduces the investigator and statistician to monitoring procedures in clinical research. Clearly presenting the necessary background with limited use of mathematics, this book increases the knowledge, experience, and intuition of investigations in the use of these important procedures now required by the many clinical research efforts. ..The author provides motivated clinical investigators the background, correct use, and interpretation of these monitoring procedures at an elementary statistical level. He defines terms commonly used such as group sequential procedures and stochastic curtailment in non-mathematical language and discusses the commonly used procedures of Pocock, O’Brien–Fleming, and Lan–DeMets. He discusses the notions of conditional power, monitoring for safety and futility, and monitoring multiple endpoints in the study. The use of monitoring clinical trials is introduced in the context of the evolution of clinical research and one chapter is devoted to the more recent Bayesian procedures. ..From the reviews:.."The author has a wealth of experience in this area and this is demonstrated thr | 出版日期 | Book 2006 | 关键词 | Area; Mathematica; Statistica; evolution; group; knowledge; language; mathematics; medicine; monitor; monitori | 版次 | 1 | doi | https://doi.org/10.1007/0-387-27782-X | isbn_softcover | 978-0-387-27781-3 | isbn_ebook | 978-0-387-27782-0 | copyright | Springer-Verlag New York 2006 |
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