Titlebook: Statistical Genomics; Methods and Protocol Ewy Mathé,Sean Davis Book 2016 Springer Science+Business Media New York 2016 sequence data forma

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The Gene Expression Omnibus Databaseand other functional genomics data sets. Created in 2000 as a worldwide resource for gene expression studies, GEO has evolved with rapidly changing technologies and now accepts high-throughput data for many other data applications, including those that examine genome methylation, chromatin structure

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土坯

Working with Oligonucleotide Arraysogical events of interest, like gene expression and allele-specific abundances. Here, we present a summary of the theory behind microarray data preprocessing for expression, whole transcriptome and SNP designs and focus on the computational protocol used to obtain processed data that will be used on

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Practical Analysis of Genome Contact Interaction Experiments between genomically distant loci. By bringing genomically distant functional elements such as enhancers and promoters into close proximity, these interactions play a key role in regulating gene expression. Some of these interactions are dynamic, that is, they differ between cell types, conditions a

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Variant Calling From Next Generation Sequence Dataes of various diseases. This chapter describes the use of freely available software to align next generation sequencing reads to a reference and then to use the resulting alignments to call, annotate, view, and filter small sequence variants. The suggested variant calling workflow includes read alig

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