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Titlebook: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging; Anna Siri Luthman Book 2018 Springer Nature Switzerla

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书目名称Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging
编辑Anna Siri Luthman
视频video
概述Nominated as an outstanding Ph.D thesis by the University of Cambridge, Cambridge, UK.Shows that multiplexed biomedical fluorescence imaging could enable highly sensitive and specific diagnosis, provi
丛书名称Springer Theses
图书封面Titlebook: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging;  Anna Siri Luthman Book 2018 Springer Nature Switzerla
描述This book describes the design, development, characterisation and application of two novel fluorescence imaging instruments based on spectrally resolved detector arrays (SRDAs). The simplest SRDA is the standard colour camera, which integrates a Bayer filter array of red, green and blue colour filters to replicate the colour sensing capability of the human eye. The SRDAs used in this book contain many more colours, ranging from 16 to over 100 colour channels. Using these compact, robust and low-cost detectors for biomedical applications opens new avenues of exploration that were not possible before, in particular, the use of spectral imaging in endoscopy. The work presented shows for the first time that not only can this new type of camera be used for fluorescence imaging, but also that it is able to resolve signals from up to 7 different dyes – a level of multiplexing not previously achieved in tissue with such compact and robust equipment. Furthermore, it reports the application of abimodal endoscope performing both reflectance and fluorescence imaging using these cameras in an ex vivo pig oesophagus model..
出版日期Book 2018
关键词Hyperspectral Imaging; Multispectral Imaging; Spectrally Resolving Detector Arrays; Camera Calibration;
版次1
doihttps://doi.org/10.1007/978-3-319-98255-7
isbn_softcover978-3-030-07473-9
isbn_ebook978-3-319-98255-7Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer Nature Switzerland AG 2018
The information of publication is updating

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Wide-Field fHSI with a Linescan SRDA,n and fluorescence spectra. Spectral imaging may, for example, be used to extract a multiplexed signal from endogenous tissue chromophores or from exogenously administered fluorescent contrast agents, via separation of their absorption and/or emission spectra.
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Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging
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