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Titlebook: Source Control; A Guide to the Manag Moshe Schein (Professor of Surgery),John C. Marsha Book 2003 Springer-Verlag Berlin Heidelberg 2003 So

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Introductionific antimicrobial therapy did not become practical until World War II and the ensuing decades [.–.]. Successful modulation of the host response that infection elicits remains a largely unfulfilled dream, — although recent promise has been shown by a variety of strategies [., .].
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Deciding on the Extent of Surgical Therapyted with future intervention. • The more extensive the initial intervention, the greater the challenge of subsequent reconstruction: the optimal intervention is that which accomplishes the source control objectives in the simplest manner.
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Definitive Versus Temporizing Therapye that the procedure be . with the knowledge that a subsequent procedure will be required,or the choice may be . with the procedure designed to both control the source but also manage the underlying disease. • The judgment to select a temporizing versus a definitive procedure requires an integrated assessment of
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Consequences of Failed Source Controlrformed poorly or with poor timing. • Leaving the abdomen open is a viable (and often necessary) adjunct to surgical management of recurrent intra-abdominal infection. • Systemic consequences of failed source control include nosocomial infections, nutritional and metabolic disorders, and multiple organ dysfunction syndrome.
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surgical infections: to control the source, focus on the soSource control is the key to the management of surgical infections. Surgical decision making is based on the marriage of evidence from clinical studies, inferences from biology, and the elusive component of surgical experience; this book co
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Introductionrt trace their origins to the work of such pioneers as Alfred Blalock in the early twentieth century, who established that shock reflected an absolute or relative intravascular volume deficit, rather than a severe fright [.]. The antibacterial activity of penicillin was identified by Fleming in the
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Invited Commentaryrated the major concepts and beliefs underlying the rationale for efficient and effective source control of infectious processes. A major implication of this overview is that primary surgical source control remains unproven by prospective randomized controlled trials (RCTs) and, as such, is in large
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