Titlebook: Social Justice and Education in the 21st Century; Research from South Willie Pearson Jr.,Vijay Reddy Book 2021 The Editor(s) (if applicabl

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ccur in identified gene modules, and the length of identified .-regulatory regions. Our method allows for the generation of synthetic promoter libraries with increased level of specificity and facilitates the selection of promoters that are highly active only under predefined gene expression profile

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ccur in identified gene modules, and the length of identified .-regulatory regions. Our method allows for the generation of synthetic promoter libraries with increased level of specificity and facilitates the selection of promoters that are highly active only under predefined gene expression profile

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Elizabeth Fairs building blocks to construct novel promoter sequences with varying activities. Bioinformatics analysis of synthetic promoter’s TFRE compositions is then performed to determine how differing relative TFRE abundances explain variations in relative promoter activities. This information is used to der

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Vijay Reddy,Bongiwe Mncwangocontrolling CRISPR effectors in heterologous systems, including mammalian cells..Here, we review the diverse applications of Acrs in mammalian cells and organisms and discuss the underlying engineering strategies. These applications include (i) persistent blockage of CRISPR-Cas function to create wr

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Fabian Arends,Lolita Winnaar,Catherine Namome(DIT). This obligatory DIT is mainly due to the energy cost of protein and fat synthesis but, in addition to this, there is an adaptive component of DIT that helps maintain body energy content (i. e. body weight) by dissipating the metabolizable energy consumed in excess of the requirements for main

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Selvarani Moodley to associate in a dynamic manner with a variety of partner proteins enables TRPC3 to serve coordination of multiple downstream signaling pathways and control of divergent cellular functions. Here, we summarize current knowledge on ion channel features as well as possible signaling functions of TRPC

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