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Titlebook: Small-Animal SPECT Imaging; Matthew A. Kupinski,Harrison H. Barrett Book 2005 Springer-Verlag US 2005 CT.SPECT.anesthesia.angiogenesis.bra

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A Multidetector High-Resolution SPECT/CT Scanner with Continuous Scanning Capability,ted tomography (CT), positron emission tomography (PET), and single-photon emission computed tomography (SPECT), all of which have a role in answering biological questions in animal models. However, techniques such as MRI and CT primarily reveal information about the organism’s structure or anatomy.
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SPECT Imager Design and Data-Acquisition Systems, small-animal SPECT imager’s configuration. We discuss the merits of detailed calibration and describe the techniques adopted in our own laboratory for direct measurement of camera and system response.
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A Micro-SPECT/CT System for Imaging of AA-Amyloidosis in Mice,eimer’s disease; amylin in Type-2 diabetes;and the prion protein in the spongiform encephalopathies such as mad cow disease. Our focus is on AA-and AL-amyloidosis, which respectively are composed of apolipoprotein A synthesized during chronic inflammation and immunoglobulin light chains synthesized by abnormal plasma cells.
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A Small-Animal SPECT Imaging System Utilizing Position Tracking of Unanesthetized Mice,solution single-photon emission tomography (SPECT)system to study unrestrained,unanesthetized mice. Others have reported development of scintillator based PET isotope probes and systems to study the brain of unanesthetized rodents +Woody, 2001, Zimmer, 2002, Vaska, 2001-.
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A Multidetector High-Resolution SPECT/CT Scanner with Continuous Scanning Capability,obtain a more complete assessment of the animals studied. Furthermore, the CT data inherently provide a map of attenuation coefficients that can be used to correct the correlated emission data for photon attenuation errors, with the goal of improving both the visual quality and the quantitative accuracy of the radionuclide image.
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Detectors for Small-Animal SPECT I, shall see in Chapter 5, the efficacy of this information transfer can be quantified and used as a figure or merit for the overall imaging system or for any component of it. Fundamentally, image quality is defined by the ability of some observer to perform some task of medical or scientific interest.
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