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Titlebook: Small-Animal SPECT Imaging; Matthew A. Kupinski,Harrison H. Barrett Book 2005 Springer-Verlag US 2005 CT.SPECT.anesthesia.angiogenesis.bra

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Imaging Dopamine Transporters in a Mouse Brain with Single-Pinhole SPECT,dopamine transporter (DAT), or reuptake site, is presumably a unique constituent of the membrane of dopaminergic nerve terminals. The integrity of the nigrostriatal projection can now be studied in vivo with radiotracers whose striatal uptake reflects binding to DATs.
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Calibration and Performance of the Fully Engineered YAP-(S)PET Scanner for Small Rodents,nce of PET. The combination of PET and SPECT techniques for small-animal studies could offer the unique possibility of developing new and interesting protocols for the investigation of many biological phenomena more effectively than with PET or SPECT modality alone.
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Book 2005of detector technologies including scintillation cameras and semi-conductor arrays, imager design and data acquisition systems, animal handling and anesthesia issues, objective assessment of image quality, and system modeling and reconstruction algorithms..
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Biomedical Significance of Small-Animal Imaging,provide models of human disease. Mice with compromised immune systems have been used for many years in studies of human tumor xenografts. The sequence of the mouse genome has been determined, and knockout mice (in which expression of a particular gene has been disabled)are available as models of var
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Detectors for Small-Animal SPECT I,hese components act together to transfer information about the object to the end user or observer, which can be a human or a computer algorithm. As we shall see in Chapter 5, the efficacy of this information transfer can be quantified and used as a figure or merit for the overall imaging system or f
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Detectors for Small-Animal SPECT II,ing the noise and other statistical factors that limit detector performance, and we saw that it was necessary to perform position estimation and other data-processing tasks that required definite statistical models. In this chapter, we introduce the statistical tools needed for these purposes.
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The Animal in Animal Imaging,ctures. Yet the value in imaging lies primarily in the benefit it brings to human lives. That potential value is determined first by studies in animals. This paper will focus on the care and handling of rodents as they make up over 90% of the animal research done. However,many of the concepts we wil
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