书目名称 | Small Molecules in Oncology | 编辑 | Uwe M. Martens | 视频video | | 概述 | Detailed coverage of the most recent developments in targeted cancer therapy using small molecules.Full discussion of preclinical studies, clinical trials, and treatment applications.Written by acknow | 丛书名称 | Recent Results in Cancer Research | 图书封面 |  | 描述 | Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the progress being made will result in significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book, written by acknowledged experts, discusses in detail the most recent developments in targeted cancer therapy using small molecules. A wide range of small molecules is covered, including, in addition to tyrosine kinase inhibitors, mTOR, proteasome, and multikinase inhibitors, among others. For each molecule, aspects such as chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. | 出版日期 | Book 2014Latest edition | 关键词 | Molecular mechanisms of cancer; Oncogenic protein kinase inhibitors; Targeted therapy; Treatment of mal | 版次 | 2 | doi | https://doi.org/10.1007/978-3-642-54490-3 | isbn_softcover | 978-3-662-51925-7 | isbn_ebook | 978-3-642-54490-3Series ISSN 0080-0015 Series E-ISSN 2197-6767 | issn_series | 0080-0015 | copyright | Springer-Verlag Berlin Heidelberg 2014 |
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