Titlebook: Small Animal Imaging; Basics and Practical Fabian Kiessling,Bernd J. Pichler,Peter Hauff Book 2017Latest edition Springer International Pub

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Concepts in Diagnostic Probe Designt agents both increase the sensitivity and the specificity of disease detection. This chapter provides an overview of the most important design considerations of contrast materials and how this affects their utility. The consequences of changes in the composition, size and other key design features

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X-Ray and X-Ray-CTSAI). Most techniques known from clinical medicine, including single- and dual-energy x-ray imaging, have been successfully ported to SAI and are the subject of this chapter. As trivial as it is, simple x-ray examinations may bring diagnostically valuable information in a variety of applications. Un

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Noninvasive Imaging for Supporting Basic Research MRSI), positron emission tomography (PET), single-photon emission computed tomography (SPECT), transmission computed tomography (CT), ultrasound (US), and optical (bioluminescence and fluorescence) imaging – and of the probes and contrast agents used with these various modalities. Newer modalities,

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Institutional Preconditions for Small Animal Imagingcedures and the international regulations for this are important issues explained here. The hygienic status of the laboratory animals used for biomedical research is essential to produce reliable results and to ensure animal and human well-being. The different hygienic levels and the housing are des

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How to Choose the Right Imaging Modalityd, which can be a significant obstacle in complex research projects that require a high number of study groups and animals. The last part focuses on the use of targeted molecular imaging. Here, different imaging modalities may be chosen if it is intended to evaluate binding affinity of a new ligand,

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X-Ray and X-Ray-CTanalogy to clinical applications, CT is considered to be of significantly higher importance as it provides more information and possibilities than conventional 2D approaches. It will therefore be covered in much more detail.