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Titlebook: Small Animal Imaging; Basics and Practical Fabian Kiessling,Bernd J. Pichler,Peter Hauff Book 2017Latest edition Springer International Pub

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书目名称Small Animal Imaging
副标题Basics and Practical
编辑Fabian Kiessling,Bernd J. Pichler,Peter Hauff
视频video
概述Provides invaluable practical guidance on the use of small animal imaging in preclinical research.Offers detailed coverage of the available imaging modalities, including newly emerging ones, with the
图书封面Titlebook: Small Animal Imaging; Basics and Practical Fabian Kiessling,Bernd J. Pichler,Peter Hauff Book 2017Latest edition Springer International Pub
描述.This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of .Small Animal Imaging. will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging..
出版日期Book 2017Latest edition
关键词Preclinical Research; Non invasive Imaging in Animals; MR contrast agents; Animal anesthesia; Establishe
版次2
doihttps://doi.org/10.1007/978-3-319-42202-2
isbn_softcover978-3-319-82522-9
isbn_ebook978-3-319-42202-2
copyrightSpringer International Publishing AG 2017
The information of publication is updating

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Noninvasive Imaging for Supporting Basic Research and rats) has emerged as a critical component of preclinical biomedical research. It allows serial assay of rodent models of human cancer and other diseases over the entire natural history of the disease process and monitoring of the effectiveness of treatment or other interventions. With the ongoi
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Non-invasive Imaging in the Pharmaceutical Industryable levels whilst productivity is declining. It is critical to both improve efficiency of the drug discovery and development process and to increase success rates, with better predictivity from preclinical to clinical investigation (Kola 2008). Imaging provides unique tools to improve efficiency, p
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Designing a Small Animal Imaging Centerhere are very few imaging devices that are appropriate to place on a laboratory bench top and use right out of the box without further integration, for example, a microscope. Most systems require training of users and a specialized environment for handling data and animals. Use of animals requires a
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Noninvasive Small Rodent Imaging: Significance for the 3R Principless is not only an ethical imperative but also a challenging and evolving area of research. Noninvasive imaging can refine in vivo experimentation by using alternative readouts which represent early disease state or adverse drug effects and which allow harmful progress to be detected. This is in contr
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Institutional Preconditions for Small Animal Imagingoratory animals. The planning and designing of the central laboratory animal facility or the experimental laboratory animal facility nearby the imaging facility is described. The different housing systems for laboratory animals like plastic cages, filter tops (micro-isolators) or individually ventil
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How to Identify Suitable Molecular Imaging Biomarkersopment. Addressing a relevant biomedical question, selecting the right target and the optimisation of ligand binding as well as pharmacokinetic parameters in preclinical models are the crucial steps before a suitable imaging agent can enter the clinical evaluation. General concepts for the selection
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