Titlebook: Skin Langerhans (Dendritic) Cells in Virus Infections and AIDS; Yechiel Becker Book 1991 Kluwer Academic Publishers 1991 AIDS.HIV.Herpes s

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tten by Lady Mary Montagu on April 1, 1717 in Adrianopole, Turkey: "The small-pox, so fatal, and so general amongst us, is here entirely harmless by the invention of ingrafting, which is the term they give it. . . The old woman comes with a nut-shell full of the matter of the best sort of small-pox

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Langerhans Cells in Tumour Development and Regressiontimate answers to these questions will depend on future studies examining the ability of Langerhans cells to process and present tumour antigens and on their capacity to generate immune responses. Such investigations in part will need to be performed on Langerhans cells extracted from neoplastic lesions.

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Dendritic Cells in the Epidermis and the Lymph Nodes — A Review the past decade about the structure and function of Langerhans cells, particularly regarding the functional relationship between Langerhans cell and other dendritic cell subsets in the lymph nodes and the epidermis. The role of Langerhans cells may not only be restricted to that of regular antigen-

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Monoclonal Antibodies to Langerhans Cells in Man and Experimental Animalsendent immune responses. Langerhans cells can leave the skin and will enter draining lymph nodes as veiled cells whereafter they can be found as interdigitating cells in the T-dependent areas of the lymph node and also of other lymphoid organs. Although these cells, which are the . equivalent of the

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Detection of Langerhans Cells with Monoclonal Antibodies the membranes of Birbeck granules and related structures. Using this antibody (Lag), we could identify LC in normal various tissues; these cells were in the skin, stratified squamous mucosal epithelia, lymph nodes, and the thymus. Lag did not react with monocytes, tissue macrophages, lymphoid dendr

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Epidermal Dendritic Cells in Immunodeficient Micefor the viable motheaten, beige, rhino or nude mutations. These mutations cause various types of immunodeficiencies associated with abnormalities in skin structure. At one month of age viable motheaten (..) mice possess normal numbers of LC compared with control heterozygotes. However by five weeks,

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Langerhans Cells in Tumour Development and Regressioncinogens and ultraviolet light-induced cutaneous tumours suggest that alteration in Langerhans cell number and function is an important feature of the early development of experimental skin tumours. This appears associated with activation of suppressor cells via I-J restricted epidermal antigen-pres

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Epidermal Dendritic Cells in Aged C57BL/6 J MICEns was investigated in old mice. Langerhans cell (LC) and Thy-1. dendritic epidermal cell (Thy-1.DEC) density was found to decrease with age. This decrease correlated with an impairment in epidermal cell function as assessed . by the skin-lymphocyte reaction assay and by measuring the ability of epi