| 书目名称 | Single Domain Antibodies | | 副标题 | Methods and Protocol | | 编辑 | Dirk Saerens,Serge Muyldermans | | 视频video | | | 概述 | Features methods of selection, expression, improvement, and library construction of single domain antibodies.Includes step-by-step instruction that has been tested in labs around the world.Provides ke | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications. In .Single Domain Antibodies: Methods and Protocols., expert researchers examine single variable domain antibody fragments, referred to as VH, VL, VHH or VNAR. These fragments are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost. Written in the highly successful .Methods in Molecular Biology.™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. | | 出版日期 | Book 2012 | | 关键词 | Heavy chain antibodies; Single variable domain; V-NAR; VHH; sdAbs; antibodies | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-61779-968-6 | | isbn_softcover | 978-1-4939-5915-0 | | isbn_ebook | 978-1-61779-968-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC 2012 |
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发表于 2025-3-21 19:37:12
