Titlebook: Simian Immunodeficiency Virus; Norman L. Letvin,Ronald C. Desrosiers Book 1994 The Editor(s) (if applicable) and The Author(s), under excl

Bereavement

Pathology of Simian Immunodeficiency Virus Induced Disease,tives to the human immunodeficiency virus (HIV; C. etal. 1987; F. et al. 1987; H. et al. 1989). In their natural hosts, which include sooty mangabeys (.; F. et al. 1986; L. et al. 1986), African green monkeys (.; D. et al. 1988; K. et al. 1985), mandrills .; T. et al. 1988), white-crowned mangabeys

铁塔等

SIVsmmPBj14: An Atypical Lentivirus,cy virus (HIV), the most relevant model is infection of macaque monkeys with simian immunodeficiency viruses (SIVs). In various macaque species the majority of SIV isolates exhibit a pathogenicity which varies from development of AIDS-like disease and death within 6–12 months, such as SIV. (Z. et al

歹徒

Conserved Framework of Envelope Glycoproteins Among Lentiviruses,the cell membrane with cellular receptors, they membrane fusion to allow virus entry, and they constitute a major the immune response. In the case of HIV-1, as well as that lentiviruses, comparisons of amino acid sequences among variou isolates have shown that envelope glycoproteins consist of a suc

Lipoprotein

乱砍

Comparison of Regulatory Features Among Primate Lentiviruses,t al. 1984; L. et al. 1984; C. et al. 1986). Since that time, besides the human immunodeficiency viruses (HIV-1 and HIV-2), molecular isolates of simian immunodeficiency viruses (SIVs; D. 1990), as well as related viruses in cattle, cats, sheep, and goats, have been obtained. For HIVs and SIVs, exte

Confound

种族被根除

CD4+ T Cell Responses to Simian Immunodeficiency Virus,ze endogenous antigen in association with MHC class I molecules and display cytotoxic activity against infected or peptide-pulsed target cells. Although these cytotoxic T lymphocytes (CTL) have usually been described following infection with viruses or intracellular bacteria, they can also be induce

易受刺激

The SIVmac Specific Cytotoxic T Lymphocyte Response in the Acutely Infected Rhesus Monkey,ne responses that block initial virus spread are likely to be central mechanisms for containing HIV infections. It is therefore important to elucidate the virologic and immunologic events that occur immediately following HIV infection. However, since the acutely infected person comes to clinical att

逃避系列单词

Envelope Sequence Variation, Neutralizing Antibodies, and Primate Lentivirus Persistence, the primary neutralizing antibody response of the host is directed at linear versus complex epitopes or to V3 versus non-V3 determinants. Neutralization escape mutants appear to arise during the course of infection of single individuals, but the variable regions primarily responsible for this escap

grandiose

Towards a Vaccine Against AIDS: Lessons from Simian Immunodeficiency Virus Vaccines,therapeutic approaches could be assessed. A wide range of mammals, including several species of non-human primates, were inoculated with strains of HIV-1 (G. et al. 1986). It soon appeared that only chimpanzees and gibbon apes were susceptible to infection by HIV-1. However, their use in AIDS resear