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Titlebook: Short-Term Bioassays in the Analysis of Complex Environmental Mixtures IV; Michael D. Waters,Shahbeg S. Sandhu,Stephen Nesnow Book 1985 Sp

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书目名称Short-Term Bioassays in the Analysis of Complex Environmental Mixtures IV
编辑Michael D. Waters,Shahbeg S. Sandhu,Stephen Nesnow
视频video
丛书名称Environmental Science Research
图书封面Titlebook: Short-Term Bioassays in the Analysis of Complex Environmental Mixtures IV;  Michael D. Waters,Shahbeg S. Sandhu,Stephen Nesnow Book 1985 Sp
描述With this proceedings of the fourth symposium on complex mixtures, we continue to revise and extend our knowledge of genetic methods for the evaluation of chemical mixtures in the environment. The early chapters of this volume are devoted to new bioassay techniques that are directly applicable to the monitoring of environments contaminated with genotoxic chemicals. Microbiological methods have been further refined to meet the special needs of atmospheric monitoring so that very small samples may now be efficiently tested. New in situ methods utilizing green plants actually avoid many of the usual difficulties of sample collection and preparation and offer special advantages in monitoring wastewater, sludges, and hazardous wastes. Insects also are being employed very effectively in the evaluation of gaseous air pollutants in controlled laboratory investigations. Increased emphasis has been placed on a comprehensive assessment of the potential of complex mixtures t9 cause various kinds of genetic damage. New assays for chromosome structural and numerical aberrations in mammalian cells in vitro have been developed and are being applied in laboratory studies. Efforts to link tests for
出版日期Book 1985
关键词Potential; cancer; environment; research; risk assessment; toxicity
版次1
doihttps://doi.org/10.1007/978-1-4615-7849-9
isbn_softcover978-1-4615-7851-2
isbn_ebook978-1-4615-7849-9
copyrightSpringer Science+Business Media New York 1985
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Anaphase Aberrations: An , Test for Assessing the Genotoxicity of Individual Chemicals and Complex M of . and . test systems have been proposed, while the aa test has gone unexploited. On the other hand, the micronucleus test (MNT) has gained wide acceptance, even though it measures only the final events of anaphase damage (Schmid, 1982) and is considerably less sensitive than the aa test for quantitating . chromosome damage.
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Correlation Between , Tumorigenesis and , Cytotoxicity in Cho and V79 Cells after Exposure to Minera; Baris et al., 1978). Substitutes for asbestos are currently being sought, but unfortunately the very properties (durable thin fibers) that provide insulation from high temperature are also likely to enhance the substitute’s tumorigenesis.
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Anaphase Aberrations: An , Measure of Genotoxicityficance as predictors of risk to whole- animal systems. The purpose of the investigation reported here was to address that question by comparing the results of one short-term . assay with long-term biological effects.
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Generation and Characterization of Complex Gas and Particle Mixtures for Inhalation Toxicologic Studiratory morbidity and mortality associated with serious air pollution exposure excursions. Yet there is little doubt that during severe episodes such as those that occurred in London in 1952 or in Donora, PA in 1948 some components present in the air were responsible for the observed respiratory- related illnesses and deaths.
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Keynote Address. We began a decade ago with a single chemical-single medium mentality and conducted excellent research in this mode. Until the mid-1970’s, we thought that the environment could be protected if we controlled a few air pollutants and a few water pollutants. Until recently, we thought the effects of a
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