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Titlebook: Short-Term Bioassays in the Analysis of Complex Environmental Mixtures II; Michael D. Waters,Shahbeg S. Sandhu,Stephen Nesnow Book 1980 Sp

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Detection of Organic Mutagens in Water Residuesion induced by these samples was equivalent to malignant transformation as verified in nude mice. In these studies, quantitation of mutagenic and transformation responses were complicated by the toxicity and heterogeneity of the complex residue mixtures.
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Bioassay of Particulate Organic Matter from Ambient Airrn (Kotin and Falk, 1963; Carnow and Meier, 1973). The first bioassays used to evaluate complex ambient air samples were whole-animal carcinogenesis bioassays (Leiteret al., 1942; Hueper et al., 1962). In these studies, organic extracts of urban particulate matter were found to be carcinogenic in ro
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