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Titlebook: Sex Chromosomes and Sex-linked Genes; Susumu Ohno Book 1966 Springer-Verlag Berlin Heidelberg 1966 Chromosom.Linke.Sex

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The Consequences of Y-autosome Translocation and the XO as the Normal Female of Certain Mammalian Spn does not handicap bearers of X-autosome translocation. This type persisted in certain species and produced the XY.Y./XX scheme of the sex-determining mechanism. In this chapter, two unusual sex-determining mechanisms which are produced as a result of Y-autosome translocation shall be discussed.
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Elucidation of So-called Sex-determining Factorsg factors on the other member of the sex chromosome pair. Yet, the exact nature of so-called sex-determining factors remains a riddle. While sex-linked genes are Mendelian genes which behave in a predictable manner, the sex-determining factors are elusive entities which have not permitted close scru
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Time and Place of Action of Sex-determining Factors in Ontogenynetic constitutions, different somatic cell types in different parts of the body perform different functions. This is because many of the genes are turned on only in certain somatic cell types. The gene loci for component polypeptides of hemoglobin function only in erythropoietic cells. Skin cells a
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Conservation of the Original X and Homology of the X-linked Genes in Placental Mammalstal mammals gave the identical DNA value of 7.0 × 10. mg per diploid nucleus. It then became apparent that in this class extensive speciation from a common ancestor was accomplished almost exclusively by allelic mutation of individual gene loci with little or no change in the total number of gene loci.
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Conservation of the Original Z-Chromosome by Diverse Avian Species and Homology of the Z-linked Geneests that the Z-chromosome of this genome lineage is very ancient in its origin. It appears that the same primitive Z has persisted in its entirety not only in diverse avian species, but also in diverse ophidian species of today.
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The Basic Difference in Constitution between the Mammalian X and the Drosophila Xe themselves to a hemizygous existence in the heterogametic male sex. The hemizygous existence for all the genes on the X should be very perilous since monosomy for even the smallest autosome (only one-fourth the size of the X) is apparently lethal in man.
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The Conservation of the Original X and Dosage Compensation in the Face of X-polysomympensation mechanism is universal to all the placental mammals in a qualitative as well as a quantitative sense in that the aim is to preserve only one original X in the functional state in each diploid somatic cell under all the normal and abnormal conditions.
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Three Different Consequences of X-autosome Translocationnit clearly reveals that the type of X-autosome translocations which split the original X into two separate halves has always been severely deteriorative to speciation, and that these translocations were eliminated as they arose.
发表于 2025-3-25 02:25:19 | 显示全部楼层
Time and Place of Action of Sex-determining Factors in Ontogenye, insulin, is activated only in Langhans islet cells of the pancreas. The above examples are given in order to demonstrate that every gene with a specialized function has a particular somatic cell type in which to express itself.
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