Titlebook: Sex Chromosomes and Sex-linked Genes; Susumu Ohno Book 1966 Springer-Verlag Berlin Heidelberg 1966 Chromosom.Linke.Sex

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Polyphyletic Evolution of Vertebratesment of the homogametic sex was conserved in its entirety. The differentiation was accomplished exclusively at the expense of the element which was elected to be the determiner of the heterogametic sex, the Y or the W.

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Conservation of the Original X and Homology of the X-linked Genes in Placental Mammals series of polyploidization of the original vertebrate genome occurred in ancient times. Once the chromosomal sex-determining mechanism was well established, the genome of that lineage was stabilized, and no further gene duplication by polyploidization was possible. Indeed, diverse species of placen

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The Basic Difference in Constitution between the Mammalian X and the Drosophila Xme a highly specialized male-determiner, having but one function namely to induce the indifferent embryonic gonad to develop as testis. The consequence of this specialization by the Y was that almost all of the original Mendelian genes which had been maintained by the X-chromosome, had to accommodat

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The Conservation of the Original X and Dosage Compensation in the Face of X-polysomyuals the number of X-chromosomes present minus one. The dosage compensation mechanism which nullifies the genetic disparity between the male and the female also serves to minimize the detrimental consequences of X-polysomy. But when this rule is viewed against the broad background of knowledge of th

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