Titlebook: Severe Asthma in Children and Adolescents; Mechanisms and Manag Erick Forno,Sejal Saglani Book 2020 Springer Nature Switzerland AG 2020 sev

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Management of Acute, Severe, and Life-Threatening Exacerbations are costly. While severe (requiring emergency room and hospital-based care) and life-threatening (with impending or established respiratory failure requiring intensive care unit-based care) exacerbations can occur in any child with asthma, children with more severe chronic asthma and those with a r

ornithology

Severe Asthma During Adolescence and the Transition to Adulthood Adolescents comprise another important and vulnerable population, in whom asthma severity may vary and many other factors, especially social influences, may affect asthma control. In this chapter we will discuss current knowledge of the natural history of severe asthma during adolescence, risk fact

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Basic Mechanisms Underpinning Severe Childhood Asthmay in the majority of patients with maintenance inhaled steroid therapy. However, there is a small group of children with very severe disease that remain poorly controlled, with frequent exacerbations despite maximal doses of inhaled steroids and, in some cases, despite maintenance systemic steroids.

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Genomics and Pharmacogenomics of Severe Childhood Asthma an important key to understanding the underlying disease mechanisms. Heritability is higher for childhood compared to adult asthma, and genetics also seem to be partly responsible for determining symptom severity, suggesting that genetic studies might be particularly relevant in relation to severe

Kidney-Failure

Special Considerations for the Management of Severe Preschool Wheezehildren has allowed for more evidence-based approaches. The purpose of this chapter is to provide the diagnostic approach to a preschool child that presents with wheezing, review the different presenting phenotypes, and review the available literature for management strategies.

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Management of Medication Side Effects and Complications effects and adverse events associated with these medications, risk factors associated with such events, appropriate testing, and considerations for the management of complications that may arise from the use of these medications in children.