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Titlebook: Serological Cancer Markers; Stewart Sell Book 1992 Springer Science+Business Media New York 1992 antigen.breast cancer.cancer.carcinoma.ce

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书目名称Serological Cancer Markers
编辑Stewart Sell
视频video
丛书名称Contemporary Biomedicine
图书封面Titlebook: Serological Cancer Markers;  Stewart Sell Book 1992 Springer Science+Business Media New York 1992 antigen.breast cancer.cancer.carcinoma.ce
描述The purpose of this book-the fourth volume of a series on Can­ cer Markers-is intended to provide an updated "status report" on today‘s use of cancer markers in the diagnosis and monitoring of can­ cer, with an emphasis on cancer markers detected in the serum. It has been 7 years since the publication of the last volume in this series. The 1980, 1982, and 1985 volumes covered the development of cancer markers, not only in their roles of unraveling the basic biology of can­ cer, but also as increasingly important players in the management of patients with cancer. During the last 7 years we have seen the applica­ tion of a number of markers identified by monoclonal antibodies, as well as the beginnings of the use of genetic markers defined by mo­ lecular probes. Measurements of oncogenes in tissues or cells prom­ ise many applications for the future, but as yet, these genes have not shown to be useful as serum markers of cancer. The commercial interest in serum markers for cancer, particu­ larly for the diagnosis and monitoring of tumor patients, is indicated in Chapter 24 by Owen, where the total worldwide market for cancer markers is projected to increase from $148 million in 1988
出版日期Book 1992
关键词antigen; breast cancer; cancer; carcinoma; cell; embryo; gastrointestinal cancer; hormones; leukemia; lymphom
版次1
doihttps://doi.org/10.1007/978-1-4612-0401-5
isbn_softcover978-1-4612-6745-4
isbn_ebook978-1-4612-0401-5
copyrightSpringer Science+Business Media New York 1992
The information of publication is updating

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978-1-4612-6745-4Springer Science+Business Media New York 1992
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,CA 15–3 Assay for the Detection of Episialin,um. Such markers are commonly used for the management of disease in cancer patients. For breast cancer, several assays have been developed based on MAbs against a sialomucin called episialin. These assays appear to be useful tools for monitoring breast cancer, since they show a higher sensitivity than the commonly used CEA assay.
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,Clinical Applications of CA 15–3, putative breast cancer markers, only a few have been found to have sufficient sensitivity and specificity to be useful clinically. Of these, carcinoembryonic antigen (CEA) has been the most commonly used and has been considered the “gold standard.”
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Alpha-Fetoprotein in the 1990s,eening system for early detection of hepatocellular carcinomas, although AFP measurement itself is included in this system (Okuda, 1986; Liaw et al., 1986; Regan, 1989). Thus, this is not to deny the value of AFP as a marker of hepatocellular carcinoma. On the other hand, it is now possible to resto
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Sex-Associated Hormones, The detection of specific sex steroid hormone receptor proteins in hormone-dependent tumors has enhanced our understanding of tumor Biology and the mechanism of endocrine therapy. Aside from carcinomas of prostate, breast, and the female reproductive organ, many solid organs have been tested for th
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Tissue Polypeptide Antigen and Specific TPA,ogression has been studied for several years (Björklund, 1980; Lüthgens and Schlegel, 1980, 1985; Skryten et al., 1981; Inoue et al., 1985; Salvati et al., 1985). Generally there is an inverse relationship between TPA level and a favorable prognosis (Björklund, 1980; Lüthgens and Schlegel, 1980, 198
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Tumor-Associated Carbohydrate Markers,(Rosenfelder et al., 1977), except a few cells in spleen and testis (Hakomori et al., 1980). The concept that TAAs are often carbohydrates evolved only after successful application of the monoclonal antibody (MAb) approach in analysis of TAAs expressed in human cancers. During the past decade, studi
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