| 书目名称 | Senescence Back and Forth | | 编辑 | Urs Nydegger,Thomas Lung | | 视频video | | | 概述 | Brings new insights into senescence.Triggers interest into how to deal with frailty.Starts out to explore the plant and animal kingdoms to answer questions human aging needs for understanding | | 图书封面 |  | | 描述 | .This book is about lifelong ageing of humans. The basic biochemical and genetic mechanisms remain ill known, and differ among individuals. The book starts out to explore the plant and animal kingdoms to answer questions human ageing needs for understanding...First, we come to scrutinize time running out and what ‘normal’ means with impacts on the genome and on protein half- lives and function. Ageing goes beyond biochemical skid treated by geroprotector drugs, including biosimilars; albeit early diagnosis with standard medical laboratory assays, here addressed, sheds light with focus on basic research. Modern tools, including machine learning, and DNA technology, e.g. genomics, have already provided for unanticipated insights..The chapters then turn around senescence of the entire organism based on variable ageing of single organs embedded in neuronal networks . Psychological stress factors, dementia opposed to vigilance, and distinction of ageing from overt disease arecontrasting in humans and are opposed in the book. Senescence, seen as a one way track may be reverted into rejuvenation, made possible by insights into immunosenescence and genomic approaches...Risk management in h | | 出版日期 | Book 2023 | | 关键词 | ageing; senescence; methylated DNA; sarcopenia,; epigenetic clock; RNA; centenarian; dementia | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-031-32276-1 | | isbn_softcover | 978-3-031-32278-5 | | isbn_ebook | 978-3-031-32276-1 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 16:41:04
