| 书目名称 | Self and Nonself |
| 编辑 | Carlos López-Larrea |
| 视频video | |
| 概述 | Covers different aspects of the emergence of immune systems in the evolution of life.Focuses on the origin of the immune response during the development of multicellularity.Presents an integrated view |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture “Immunological Recognition of Self” emphasizing the central argument of immunological tolerance in “How does the vertebrate organism recognize self from nonself in this the immunological sense—and how did the capacity evolve.” The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself. Even in the context of the limited number of metazoan phyla that have been studied in detail, we can now describe many of the alternative mechanism of immune recognition that have emerged at varying points in phylogeny. Two different arms—the innate and adaptive immune system—have emerged at different moments in evolution, and they are conceptually different. The ultimate goals of immune biology include reconstructing the molecular networks underlying immune processes. |
| 出版日期 | Book 2012 |
| 关键词 | Immunology; López-Larrea; Self-Nonself Recognition |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4614-1680-7 |
| isbn_softcover | 978-1-4939-4343-2 |
| isbn_ebook | 978-1-4614-1680-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 16:54:19
