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Titlebook: Selenium; Its Molecular Biolog Dolph L. Hatfield,Marla J. Berry,Vadim N. Gladyshe Book 20062nd edition Springer-Verlag US 2006 AIDS.Diabete

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Xin Gen Lei,Wen-Hsing Chengnd firewalls have visible benefits and remain virtually unnoticed during normal operations, the situation is different with intrusion detection sensors. State-of-the-art IDSs produce hundreds or even thousands of alerts every day. Unfortunately, almost all of these alerts are false positives, that i
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Mammalian and other eukaryotic selenocysteine tRNAsty at position 34 (designated Um34), appears to be responsible for the expression of selenoproteins that have roles in stress-related phenomena and are highly dependent on selenium for their expression. Several new observations regarding Sec biosynthesis, which occurs on its tRNA, have also been rec
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SECIS RNAs and K-turn binding proteins. A survey of evolutionary conserved RNA and protein motifspropose here that the SECIS RNA must represent a K-turn variant with regard to the limited structural differences that distinguish it from consensus K-turns. Work by others showed that ribosomal protein L30 also binds the SECIS RNA in a specific manner. L30 and SBP2 are members of a family of protei
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The importance of subcellular localization of SBP2 and EFsec for selenoprotein synthesisSs and NESs and may be particularly important for final export of a stable protein/mRNA complex from the nucleus to the cytoplasm for translation. In this context, the subcellular location of these important components of the selenocysteine incorporation machinery is as essential for proper translat
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Selenocysteine biosynthesis and incorporation may require supramolecular complexesuggests that both the biosynthesis of Sec-tRNA and the incorporation of Sec are physically coupled within supramolecular complexes that retain and coordinate the many factors required, tRNA channeling systems for the standard 20 amino acids rely on cotranslational complexes for spatial and temporal
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