书目名称 | Selective Sentinel Lymphadenectomy for Human Solid Cancer |
编辑 | Stanley P. L. Leong,Yuko Kitagawa,Masaki Kitajima |
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概述 | First book of its kind to apply the concept of sentinel lymph nodes to the majority of human solid cancer.Provides not only rich illustrations from experts in the field as how to successfully perform |
丛书名称 | Cancer Treatment and Research |
图书封面 |  |
描述 | .In human solid cancer, the lymph node (LN) status is the most important prognostic indicator for the clinical outcome of patients. Recent developments in the sentinel lymph node (SLN) concept and technology have resulted in the application of this revolutionary approach to define the first draining or SLN to which the cancer may have metastasized. The underlying thesis in solid cancer biology is that metastasis generally starts in an orderly progression, spreading through the lymphatic channels to the SLN in the nearest LN basin. Thus, the logical approach is to harvest that specific SLN for thorough analysis. Because a tumorfree SLN is usually associated with a negative residual LN basin, a negative SLN is an excellent indication that micrometastasis has not occurred in the regional LNs. When the SLN is involved, it is unknown whether or not metastasis is limited only to the SLN or if the disease has spread to the remainder of the nodal basin. For this reason, if a SLN is positive, a complete lymph node dissection is recommended. Therefore, selective sentinel lymphadenectomy (SSL) should be considered as a staging procedure so that patients with negative SLNs (about 80%) may be s |
出版日期 | Book 2005 |
关键词 | Staging; breast cancer; cancer; cancer treatment; carcinoma; cell; clinical trial; gastric cancer; melanoma; |
版次 | 1 |
doi | https://doi.org/10.1007/b101891 |
isbn_softcover | 978-1-4899-8869-0 |
isbn_ebook | 978-0-387-23604-9Series ISSN 0927-3042 Series E-ISSN 2509-8497 |
issn_series | 0927-3042 |
copyright | Springer-Verlag US 2005 |