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Titlebook: Selected Topics in Mass Spectrometry in the Biomolecular Sciences; Richard M. Caprioli,Antonio Malorni,Giovanni Sindo Book 1997 Springer S

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书目名称Selected Topics in Mass Spectrometry in the Biomolecular Sciences
编辑Richard M. Caprioli,Antonio Malorni,Giovanni Sindo
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丛书名称Nato Science Series C:
图书封面Titlebook: Selected Topics in Mass Spectrometry in the Biomolecular Sciences;  Richard M. Caprioli,Antonio Malorni,Giovanni Sindo Book 1997 Springer S
描述Many fundamental aspects of the methods used in massspectrometry are here presented by outstanding scientists, withreference to very recent developments. The principles and applicationsof electrospray, ion spray and MALDI ionization technique arepresented, together with optimised GC/MS interfacing systems and toolsfor quantitative analysis. A comprehensive treatment of moderninstrumentation for mass analysis and detection is also included. Themajor part of the book deals with bioanalytical applications topeptides, proteins, oligonucleotides, polysaccharides, lipids andplant metabolites. Several papers are devoted to the evaluation ofadduct formation between DNA and carcinogens. Environmentalapplications are also included, with examples of some specific cases..Fundamentals and applications are treated with the same degree ofdepth: the first two parts of the book therefore provide a basis forthe understanding of the biomolecular applications section. ..Audience:. Ideal for advanced graduate students of chemistry whohave learned some basic mass spectrometry. Also useful for Ph.D.students in chemistry, biology and medicine. Of value to researchersin academic and industrial laboratories
出版日期Book 1997
关键词DNA; Lipid; Mass Spectrometry; Nucleotide; Polysaccharid; Termination; proteins
版次1
doihttps://doi.org/10.1007/978-94-011-5165-8
isbn_softcover978-94-010-6171-1
isbn_ebook978-94-011-5165-8Series ISSN 1389-2185
issn_series 1389-2185
copyrightSpringer Science+Business Media Dordrecht 1997
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Optimised GC/MS interfacing systems and operating conditionsThe different methods for directly coupling a capillary column to a mass spectrometer in a compact GC/MS system are reviewed.
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Role of Internal Energy in Mass Spectrometric Fragmentationckground: the reaction rate theory and the calculation of ion abundances from reaction rates. The effect of the reaction timescale, the degree-offreedom effect and the breakdown curve is discussed. Finally, typical internal energy distributions in electron impact, metastable ions, collision induced fragmentations are shown.
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stive detail and mathematical depth provided in more comprehensive treatments of the subject. The presentation covers the mathematical laws of random phenomena, including discrete and continuous random variables, expectation and variance, and common probability distributions such as the binomial, Po
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