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Titlebook: Selected Reaction Monitoring Mass Spectrometry (SRM-MS)in Proteomics; A Comprehensive View Mahmud Hossain Book 2020 Springer Nature Switzer

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发表于 2025-3-21 17:37:13 | 显示全部楼层 |阅读模式
书目名称Selected Reaction Monitoring Mass Spectrometry (SRM-MS)in Proteomics
副标题A Comprehensive View
编辑Mahmud Hossain
视频video
概述Provides knowledge-based planning and optimized design of SRM-MS experiments and data analysis.Describes SRM-MS applications in proteomics.Covers various software and databases for SRM-MS analyses
图书封面Titlebook: Selected Reaction Monitoring Mass Spectrometry (SRM-MS)in Proteomics; A Comprehensive View Mahmud Hossain Book 2020 Springer Nature Switzer
描述.Covering a wide-ranging facet of a “gold-standard” targeted mass spectrometry (MS) method for the consistent detection and accurate quantification of preselected proteins in complex biological matrices, .Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics: A Comprehensive View. describes:.The knowledge-based development of highly efficient SRM methodology including assay workflow, selection of proteins, peptides, transitions and its validation, and quality assessment.Available bioinformatic tools – for both pre-acquisition method development and post-MS acquisition data analysis and data repositories.Various relative and absolute quantification techniques.SRM-MS’ widespread applications in biomarker development and in clinical studies, as well as in the analysis of various posttranslational modifications (PTMs).Current challenges and contemporary trends to overcome those difficulties .In addition,it features the historical development of modern-day mass spectrometry with its vivid applications and also covers basic MS instrumentation, ionization techniques, and various proteomics approaches. .Comprehensive discussion, extensive references at the end of each chapt
出版日期Book 2020
关键词proteomics; posttranslational modification; assay design; Collision induced Dissociation; peptide select
版次1
doihttps://doi.org/10.1007/978-3-030-53433-2
isbn_softcover978-3-030-53435-6
isbn_ebook978-3-030-53433-2
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

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发表于 2025-3-21 21:59:56 | 显示全部楼层
Mahmud HossainProvides knowledge-based planning and optimized design of SRM-MS experiments and data analysis.Describes SRM-MS applications in proteomics.Covers various software and databases for SRM-MS analyses
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Bioinformatics Tools for SRM-MS,searchers in the preacquisition and postacquisition analysis of SRM assays. Already designed and validated SRM assays are available from several public databases/knowledge bases like SRMAtlas, CPTAC, PeptideTracker, GPMDB, or MRMAssayDB which helps to speed up the assay development process significantly.
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SRM-MS for Posttranslational Modification Analysis, immunoprecipitation, multidimension chromatography, or the usage of multiple proteases. Phosphorylation, ubiquitination, glycosylation, acetylation, and several other PTMs in protein molecules can be detected and quantified using SRM-MS.
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