书目名称 | Selected Reaction Monitoring Mass Spectrometry (SRM-MS)in Proteomics | 副标题 | A Comprehensive View | 编辑 | Mahmud Hossain | 视频video | | 概述 | Provides knowledge-based planning and optimized design of SRM-MS experiments and data analysis.Describes SRM-MS applications in proteomics.Covers various software and databases for SRM-MS analyses | 图书封面 |  | 描述 | .Covering a wide-ranging facet of a “gold-standard” targeted mass spectrometry (MS) method for the consistent detection and accurate quantification of preselected proteins in complex biological matrices, .Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics: A Comprehensive View. describes:.The knowledge-based development of highly efficient SRM methodology including assay workflow, selection of proteins, peptides, transitions and its validation, and quality assessment.Available bioinformatic tools – for both pre-acquisition method development and post-MS acquisition data analysis and data repositories.Various relative and absolute quantification techniques.SRM-MS’ widespread applications in biomarker development and in clinical studies, as well as in the analysis of various posttranslational modifications (PTMs).Current challenges and contemporary trends to overcome those difficulties .In addition,it features the historical development of modern-day mass spectrometry with its vivid applications and also covers basic MS instrumentation, ionization techniques, and various proteomics approaches. .Comprehensive discussion, extensive references at the end of each chapt | 出版日期 | Book 2020 | 关键词 | proteomics; posttranslational modification; assay design; Collision induced Dissociation; peptide select | 版次 | 1 | doi | https://doi.org/10.1007/978-3-030-53433-2 | isbn_softcover | 978-3-030-53435-6 | isbn_ebook | 978-3-030-53433-2 | copyright | Springer Nature Switzerland AG 2020 |
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