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Titlebook: Schistosoma mansoni; Methods and Protocol David J. Timson Book 2020 Springer Science+Business Media, LLC, part of Springer Nature 2020 Schi

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书目名称Schistosoma mansoni
副标题Methods and Protocol
编辑David J. Timson
视频video
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Schistosoma mansoni; Methods and Protocol David J. Timson Book 2020 Springer Science+Business Media, LLC, part of Springer Nature 2020 Schi
描述.This volume details protocols for studying .Schistosoma mansoni..  Chapters guide readers through reviews on current drugs and drug discovery, methods to interrogate the cell biology of the worm, protocols to look at proteome level changes, prepare and work with specific proteins from .S. mansoni, .describes a drug screening, and how to test potential vaccine targets. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls...Authoritative and cutting-edge, .Schistosoma mansoni: Methods and Protocols .aims to ensure successful results in the further study of this vital field..
出版日期Book 2020
关键词Schistosomiasis; Parasitic infection; S; mansoni; drug screening method; potential vaccine targets; prote
版次1
doihttps://doi.org/10.1007/978-1-0716-0635-3
isbn_softcover978-1-0716-0637-7
isbn_ebook978-1-0716-0635-3Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2020
The information of publication is updating

书目名称Schistosoma mansoni影响因子(影响力)




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书目名称Schistosoma mansoni被引频次学科排名




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书目名称Schistosoma mansoni读者反馈学科排名




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Characterization of , Glutamate-Gated Chloride Channels,n which can be applied to the characterization of glutamate-gated chloride channels from ., a potential schistomicidal target. Here, the method is described in detail, with an emphasis on the investigation of .. GluCls.
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978-1-0716-0637-7Springer Science+Business Media, LLC, part of Springer Nature 2020
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Praziquantel: An Enigmatic, Yet Effective, Drug,uantel is briefly reviewed and a hypothesis for its mechanism proposed. This hypothesis suggests that the drug works, in part, by disrupting an interaction between a voltage-gated calcium channel (SmCav1B) and an accessory protein, SmTAL1.
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Structural and Functional Characterization of , Cathepsin B1, expression system and its purification, (2) the measurement of SmCB1 activity and inhibition in a kinetic fluorescence assay, and (3) the preparation and crystallization of SmCB1 in complex with a model vinyl sulfone inhibitor, and the determination of its crystal structure.
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A Modified ELISA Method to Evaluate the Interaction of , Proteins with Plasminogen,ant protein; competitive binding with a lysine analog demonstrated the interaction of the protein lysine residues with PLG Kringle domains. To assess the activation of . recombinant protein-bound PLG, the amidolytic activity of generated plasmin was measured using the .-Val-Leu-Lys 4-nitroanilide dihydrochloride substrate.
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