| 书目名称 | SUMO Protocols | | 编辑 | Helle D. Ulrich | | 视频video | | | 概述 | First methods collection devoted entirely to the SUMO system.Provides comprehensive practical advice from leading experts in the field.Covers a range of complementary approaches for SUMO target identi | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | Post-translational protein modifications by members of the ubiquitin family are widely recognized as important regulatory control systems for a variety of biological pathways. Their influence on eukaryotic cellular metabolism is comparable to that of other modifi- tions such as phosphorylation, acetylation and methylation. The small ubiquitin-related modifier SUMO uses a conjugation and de-conjugation system closely related to that of ubiquitin itself; yet, the functions of the SUMO system are highly diverse and largely independent of the ubiquitin system. SUMO modification controls the activity of tr- scription factors and can influence protein stability, but it also contributes to nucleo-cy- plasmic transport, chromosome segregation and DNA damage repair. As a consequence, the SUMO system pervades virtually all areas of basic molecular and cell biology, and scientists from different backgrounds, including medical researchers, are likely to enco- ter SUMO in the course of their studies. This volume, SUMO Protocols, therefore aims at presenting a collection of methods relevant to SUMO research in order to make these tools available to biochemists, molecular and cell biologists as w | | 出版日期 | Book 2009 | | 关键词 | Escherichia coli; Proteomics; Vivo; enzymes; molecular biology; regulation; saccharomyces cerevisiae; trans | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-59745-566-4 | | isbn_softcover | 978-1-61737-945-1 | | isbn_ebook | 978-1-59745-566-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2009 |
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发表于 2025-3-21 19:18:48
