书目名称 | SH2 Domains | 副标题 | Methods and Protocol | 编辑 | Kazuya Machida,Bernard A. Liu | 视频video | http://file.papertrans.cn/861/860171/860171.mp4 | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .This volume covers an array of techniques available for studying SH2 domains and phosphotyrosine signaling. The book is divided into six parts: Part I outlines the history of SH2, technology development, and cell signaling; Part II focuses on computational approaches and tools used for identification, classification, and predictions of SH2 domain binding partners; Part III details various ways to prepare the SH2 domains as experimental reagents; Part IV presents methods for structural analysis and conventional binding assays using SH2 domains; Part V describes high-throughput and proteomics approaches to aid in analyzing SH2-mediated interactions; and Part VI covers applications for SH2 domain to functional and imaging analyzes. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Cutting-edge and thorough, .SH2 Domains: Methods and Protocols. is a valuable resource for computational biologists, biochemists, structural biologists, cell bio | 出版日期 | Book 2017 | 关键词 | receptor tyrosine kinases (RTKs); phosphotyrosine signaling; cell signaling; structural analysis; conven | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-6762-9 | isbn_softcover | 978-1-4939-8295-0 | isbn_ebook | 978-1-4939-6762-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media LLC 2017 |
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