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Titlebook: SELL YOUR RESEARCH; Public Speaking for Alexia Youknovsky,James Bowers Book 20201st edition Springer Nature Switzerland AG 2020 Public spe

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ire injection of exogenous insulin, just as it does in patients with type 1 diabetes. In fact, the resistance to insulin’ s action in patients with type 2 diabetes often requires the use of large doses of insulin to achieve adequate glycemic control. The goals of insulin therapy in patients with typ
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Alexia Youknovsky,James Bowersstablative hypothyroidism after therapy for hyperthyroidism or thyroid surgery is the second most common cause. Drugs may also precipitate primary hypothyroidism, especially in people with underlying autoimmune thyroid disease (i.e., positive antithyroid antibodies). Lithium and iodine-containing dr
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m the embryogenesis of the endocrine system, the journey of the signal molecules takes them through many steps including biosynthesis, release and transport, recognition by the target cell, transduction of the message, and, finally, extinction of the signal through counterregulation, metabolism, and
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Alexia Youknovsky,James Bowersd MKK activates in turn the serine/threonine kinase MAP kinase or MAPK on the threonine and tyrosine residues of the consensus motif TXY (where T is threonine, X is glutamic acid, glycine or proline, and Y is tyrosine) [4]. Finally, activated MAPK phosphorylates diverse substrates including nuclear
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Alexia Youknovsky,James Bowers substrates including the receptor itself, leading to the activation of distinct signaling pathways. This review will focus first on the structure and biological properties of Epo, Tpo, leptin and their receptors. The second part will summarize the signal transduction pathways induced by these three
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d MKK activates in turn the serine/threonine kinase MAP kinase or MAPK on the threonine and tyrosine residues of the consensus motif TXY (where T is threonine, X is glutamic acid, glycine or proline, and Y is tyrosine) [4]. Finally, activated MAPK phosphorylates diverse substrates including nuclear
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Alexia Youknovsky,James Bowerstivation. Together with NF-kB, NF-AT, and SMADs, STATs represent one of four types of transcription factors that are rapidly translocated from cytosol to nucleus in a fashion that is dependent on phosphorylation/dephosphorylation events. This short chapter cannot comprehensively review all that is k
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