Titlebook: SCF and APC E3 Ubiquitin Ligases in Tumorigenesis; Hiroyuki Inuzuka,Wenyi Wei Book 2014 The Author(s) 2014 E3 ubiquitin ligase.F-box prote

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The Role of FBXL Subfamily of F-box Proteins in Tumorigenesis, motif and a C-terminal Leu-rich repeat (LRR) domain (Fig. 3.1). Intensive studies have revealed an oncogenic role for Skp2, but the potential roles of other FBXL subfamily members in tumorigenesis have just begun to be appreciated. In this chapter, we primarily focus on summarizing the recent genet

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The Role of FBXO Subfamily of F-box Proteins in Tumorigenesis,ning 36 F-box proteins were designated as F-box only (FBXO) proteins. It is noteworthy that the FBXO subfamily proteins have been identified to contain the F-box motif in its N-terminus and various types of functional domains in its C-terminus that mediate substrate binding. Unlike FBXW proteins wit

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Conclusions and Research Perspectives,ificant amount of experimental evidence has been generated towards understanding the biochemical features and the physiological functions of these ligases, especially their roles in tumorigenesis. In this book, we have discussed the growing list of the identified ubiquitin substrates for SCF and APC

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Green Hydrogen Supply Chains in Latin America – A Research Approach for Partnership Projects with Euimportant role in the decarbonization of the global economy because of its specific versatility. Given the recent imminent energy shortages in Europe, supply of green hydrogen becomes an even more important topic for European countries. Therefore, an informed search is required for international bus

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Integrating Renewable Resources: Grid Operations and Policy Considerations,nt grid. An overview of the electricity industry structure and the solar and wind technologies themselves are described to provide a foundation for understanding those challenges. Electricity in the U.S. is provided by more than 3000 diverse organizations. The industry’s regulatory structure exists

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