书目名称 | Role of Tyrosine Kinases in Gastrointestinal Malignancies |
编辑 | Ganji Purnachandra Nagaraju |
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概述 | This book highlights the different tyrosine kinases that are involved in gastrointestinal cancers.It describes the roles of tyrosine kinases in tumor growth and tumor cell metastasis including migrati |
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描述 | .The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy...Each chapter embedded in this book covers information pertaining to a specific tyrosine kinase and its impact on various malignancies, which is not only significant for basic and clinical research investigations but will also be valued by students at advanced undergraduate to postgraduate levels.. |
出版日期 | Book 2018 |
关键词 | Tyrosine kinases; Gastrointestinal malignancies; Tyrosine kinase receptors; Tyrosine Kinase inhibitors; |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-13-1486-5 |
isbn_softcover | 978-981-13-4640-8 |
isbn_ebook | 978-981-13-1486-5 |
copyright | Springer Nature Singapore Pte Ltd. 2018 |