Titlebook: Rodent Models of Stroke; Ulrich Dirnagl Book 2016Latest edition Springer Science+Business Media New York 2016 stroke.rodent models.modelin

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Housing in an Enriched Environment: A Tool to Study Functional Recovery After Experimental Stroke,promote improvement of lost neurological function after stroke. These observations can be mimicked in an experimental setting by multimodal stimulation provided in the concept of enriched environment. The enriched environment is a housing condition for rodents combining social interactions and senso

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Effect of Anesthesia in Stroke Models,r aspects, and function. Many animal and cellular models are utilized for these types of studies. However, anesthetics must be used for in vivo studies or at least in most animal models of cerebral ischemia. In many of these studies, there has been an intensive search for agents that are neuroprotec

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Noninvasive Brain Imaging in Small Animal Stroke Models: MRI, PET, and SPECT,se techniques are used in patients for diagnostic purposes and are now available to image the rodent brain. However, noninvasive imaging of the brain of rodents is challenging because of the size of the animals and the fact that their handling normally requires sedation or deep anesthesia to avoid s

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Noninvasive Optical Imaging in Rodent Models of Stroke,omedical research. Given the availability of specific fluorescent probes and reporter gene technologies, which allow the noninvasive visualization of a variety of pathophysiological processes. The technology might also pose an attractive research tool for preclinical stroke research. This chapter gi

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Behavioral Testing in Rodent Models of Stroke, Part II,arch includes the use of reliable tests of functional outcome. This chapter presents select behavioral tests commonly used for evaluating somatosensory, locomotor, and skilled and cognitive functions in rodent models of stroke. The methods described emphasize the value of careful quantitative and qu

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Histology and Infarct Volume Determination in Rodent Models of Stroke,s, this plethora can ultimately be reduced to a few basic methods such as histological staining, contrast-enhanced staining, immunohistochemistry, and enzyme histochemistry. In this chapter, each of these will be briefly introduced with an exemplary protocol. Since each method requires specific tiss