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Titlebook: Ribosomes; Alexander S. Spirin Book 1999 Springer Science+Business Media New York 1999 RNA.biology.biosynthesis.evolution.membrane.membran

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Elongation Cycle, Step III: Translocatione P site (Fig. 12.1, .). . is defined as an intraribosomal movement of the bound tRNA residues accompanied by the shift of the template polynucleotide relative to the ribosome. In sum, the tRNA residue of the peptidyl-tRNA moves from the A site to the P site, the deacylated tRNA is displaced from th
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Termination of Translationne of these triplets possess a cognate aminoacyl-tRNA; they all stop translation. Thus, they serve as . (Brenner, Stretton, and Kaplan, 1965; Brenner ., 1967). UAA is the most frequently used of these codons, whereas UAG is rarely used.
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Initiation of Translatione, or reinitiation of translation of the next coding sequence of the same polycistronic mRNA (in prokaryotes), or reinitiation of translation of the same monocistronic mRNA (in eukaryotes) by vacant post-termination ribosomes have evolved in living matter.
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ity. These lectures have been part of a general course on molecular biology for almost three decades, and they have undergone considerable evolution as knowledge has been pro­ gressing in this field. The progress continues, and readers should be prepared that some facts, statements, and ideas includ
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Mutual Arrangement of Ribosomal RNA and Proteins (Quaternary Structure)eases. This fundamental difference compared to viral particles is understandable, since the ribosome is a functional structure in which RNA should actively participate in interactions with external factors, and is not used for storing genetic information.
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