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Titlebook: Ribosomes; Alexander S. Spirin Book 1999 Springer Science+Business Media New York 1999 RNA.biology.biosynthesis.evolution.membrane.membran

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书目名称Ribosomes
编辑Alexander S. Spirin
视频videohttp://file.papertrans.cn/831/830176/830176.mp4
丛书名称Cellular Organelles
图书封面Titlebook: Ribosomes;  Alexander S. Spirin Book 1999 Springer Science+Business Media New York 1999 RNA.biology.biosynthesis.evolution.membrane.membran
描述This book is based on an advanced course of lectures on ribosome structure and protein biosynthesis that I offer at the Moscow State University. These lectures have been part of a general course on molecular biology for almost three decades, and they have undergone considerable evolution as knowledge has been pro­ gressing in this field. The progress continues, and readers should be prepared that some facts, statements, and ideas included in the book may be incomplete or out­ of-date. In any case, this is primarily a textbook, but not a comprehensive review. It provides a background of knowledge and current ideas in the field and gives ex­ amples of observations and their interpretations. I understand that some interpre­ tations and generalizations may be tentative or disputable, but I hope that this will stimulate thinking and discussing better than if I left white spots. The book has a prototype: it is my monograph "Ribosome Structure and Pro­ tein Biosynthesis" published by the Benjamin/Cummings Publishing Company, Menlo Park, California, in 1986. Here I have basically kept the former order of pre­ sentation ofthe topics and the subdivision into chapters. The contents ofthe chap
出版日期Book 1999
关键词RNA; biology; biosynthesis; evolution; membrane; membrane transport; molecular biology; morphology; protein;
版次1
doihttps://doi.org/10.1007/978-1-4615-7817-8
isbn_softcover978-0-306-46146-0
isbn_ebook978-1-4615-7817-8
copyrightSpringer Science+Business Media New York 1999
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978-0-306-46146-0Springer Science+Business Media New York 1999
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Morphology of the Ribosomeabout 200 to 250 Å (Fig. 5.1), and somewhat larger, from 200 to 300 Å, in the case of eukaryotic ribosomes. Ribosomes from different organisms and cells, whether prokaryotic or eukaryotic, have a strikingly similar appearance.
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Ribosomal RNAubunits. The rRNA molecules form a framework for specific positioning of ribosomal proteins in the ribosome. rRNA plays the leading role in ribosome function, participating in every aspect of protein synthesis. Therefore, it can be said that the ribosome is its RNA.
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Translational Control in Prokaryotesity of mRNA for translation and modulation of mRNA translation rate (translational level); and (3) by mRNA elimination (degradation). Although both transcription and mRNA degradation may also depend on ribosomes, only the translational level of protein synthesis regulation will be considered here.
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Ribosomes and TranslationBy 1940 Albert Claude had succeeded in isolating from animal cells cytoplasmic RNA-containing granules that were smaller than mitochondria. These granules varied from 50 to 200 μ in diameter and later Claude began calling them .. Chemical analyses indicated that Claude’s microsomes were “phospholipid-ribonucleoprotein complexes.”
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