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Titlebook: Rheumatoid Arthritis; Recent Research Adva Josef S. Smolen,Joachim R. Kalden,Ravinder N. Main Conference proceedings 1992 Springer-Verlag B

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Heat-Shock Proteins and Mycobacterial Antigensptibility and that at least some of these factors are encoded within or close to the major histocompatibility complex (MHC). In the case of rheumatological disorders, the association of HLA-B27 with ankylosing spondylitis is well-known and impressive. Of less biological impact, but certainly very si
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The Genetics of Rheumatoid Factors (RF): The V-gene Repertoire of RFs in Rheumatoid Arthritis as Ana1950 included the confirmation of Waaler’s findings by Rose and collaborators [see 50]. This period brought an appreciation of the diagnostic significance of rheumatoid factors in RA, although it was clear that there is also a group of patients with seronegative rheumatoid arthritis [50].
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Heat-Shock Proteins and Mycobacterial Antigensgnificant, is the association of HLA-DR4 and HLA-DR1 with rheumatoid arthritis. Furthermore, evidence has been put forward that the same DR4 allele contributes to the development of arthritis in Lyme borreliosis [42].
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onicarthritis and the relationshipbetween cellular processes that underlie inflammation andtissue damage. All these are dealt with in depth intheindividual contributions.Genetics studies included illustrate howstudies of HLAgenes and genes controlling the autoantibody repertoiremaybe involved. Envir
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