| 书目名称 | Rheumatoid Arthritis | | 副标题 | Recent Research Adva | | 编辑 | Josef S. Smolen,Joachim R. Kalden,Ravinder N. Main | | 视频video | | | 图书封面 |  | | 描述 | Many advances have occurred in the last 5 years especiallyin understanding genetic susceptibility factors, the role ofimmune response in chronicarthritis and the relationshipbetween cellular processes that underlie inflammation andtissue damage. All these are dealt with in depth intheindividual contributions.Genetics studies included illustrate howstudies of HLAgenes and genes controlling the autoantibody repertoiremaybe involved. Environmental factors are believed to beimportant and studies both in humans and in experimentalmodels on the role of viral andbacterial agents arecovered. The fascinating relationship betweenmicrobes,dysregulated immune responses and oncogenes are alsoexamined.Since autoimmunity is the key aspect of theimmunologicalresponse in rheumatoid arthritis, the role of antigensisre-examined as is the part played by immune T and B cells.New areas of clinical application of basic science is wellpresented in this book, forexample, in examining howmarkers of cartilage destruction may become important inmonitoring disease activity. A chapter reviewing possiblefuture novel therapies is included. | | 出版日期 | Conference proceedings 1992 | | 关键词 | Arthritis; Immungenetik; antibody; antigen; autoimmunity; bacteria; cartilage; genetics; immune response; imm | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-76189-8 | | isbn_softcover | 978-3-642-76191-1 | | isbn_ebook | 978-3-642-76189-8 | | copyright | Springer-Verlag Berlin Heidelberg 1992 |
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发表于 2025-3-21 17:35:37
