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Titlebook: Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy; A Handbook for Diagn Maria E. Suarez-Almazor,Leonard H. Calabrese Book 20

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发表于 2025-3-21 17:07:11 | 显示全部楼层 |阅读模式
书目名称Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy
副标题A Handbook for Diagn
编辑Maria E. Suarez-Almazor,Leonard H. Calabrese
视频video
概述Written in a handbook format with clinical tips for a variety of medical professionals.Discusses epidemiology, clinical manifestations, diagnosis, differential diagnosis, and treatment of rheumatic ir
图书封面Titlebook: Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy; A Handbook for Diagn Maria E. Suarez-Almazor,Leonard H. Calabrese Book 20
描述.With the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially. Management of these irAE is challenging as it requires not only consideration of the toxicity but also risk-benefit ratios with respect to the primary cancer. Several rheumatic irAE have been reported with ICI therapy including arthritis, myositis, polymyalgia-like syndromes, sicca/Sjogren-like manifestations, and several other less common systemic autoimmune features commonly associated with connective tissue disease. .This handbook provides clinicians with a comprehensive overview of the management of rheumatic irAE that develop from cancer immunotherapy. It focuses on the irAE seen with ICI, the most frequently used agents in treating cancer. It provides an overview of cancer immunology,immunotoxicity, and immunotherapies such as ICI, cytokine-based therapy, and CART. It examines the epidemiology, clinical manifestations, diagnosis, differential diagnosis, and treatment of a variety of rheumatic immune-relate
出版日期Book 2021
关键词Cancer immunotherapy and rheumatic diseases; Cancer immunotherapy and arthritis; Cancer immunotherapy
版次1
doihttps://doi.org/10.1007/978-3-030-56824-5
isbn_softcover978-3-030-56823-8
isbn_ebook978-3-030-56824-5
copyrightSpringer Nature Switzerland AG 2021
The information of publication is updating

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Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy978-3-030-56824-5
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Immunopathogenesis of Immune-Related Adverse Events from Cancer Immunotherapyorder to allow the crafting of immunosuppressive/immunomodulatory therapies which will be effective but not compromise the basic antitumoral properties of ICI-based therapies. This chapter reviews current concepts of immunopathogenesis of irAEs and appraises data from in vitro preclinical models and
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Sicca Syndromes condition often develops abruptly and is objectively quite severe. Within the reported cases, we highlight marked clinical heterogeneity with three potential patient subsets: (i) those with . sicca . systemic symptoms, (ii) those with . sicca . systemic symptoms, and (iii) and those with a flare of
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Book 2021d agents in treating cancer. It provides an overview of cancer immunology,immunotoxicity, and immunotherapies such as ICI, cytokine-based therapy, and CART. It examines the epidemiology, clinical manifestations, diagnosis, differential diagnosis, and treatment of a variety of rheumatic immune-relate
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