Titlebook: Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders; Paul C. Guest Book 2019 The Editor(s) (if applicable) and The

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Computational Approaches for Identification of Pleiotropic Biomarker Profiles in Psychiatry,f advanced computational approaches, the lack of strong individual predictors of clinically relevant outcomes, combined with the usually high dimensionality, significantly hamper the identification of such markers. Consistent with the often observed lack of diagnostic specificity of biological alter

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miRNA Regulation of Glucose and Lipid Metabolism in Relation to Diabetes and Non-alcoholic Fatty Li plays a pivotal role in cellular metabolism by targeting the key rate-limiting enzymes of relevant pathways to fine-tune control of metabolic homeostasis. Aberrant expression of these miRNAs can result in an over or under expression of those key enzymes, contributing to the etiology of diabetes and

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Circular RNAs as Potential Biomarkers and Therapeutic Targets for Metabolic Diseases,ly associated with different abnormalities that hold a key role in the emergence and progression of frequent disorders including diabetes mellitus (DM), non-alcoholic fatty liver disease (NAFLD), obesity, metabolic syndrome and cardiovascular diseases. The burden of metabolic diseases is believed to

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Deciphering Endothelial Dysfunction in the HIV-Infected Population,stration of antiretroviral drugs. This warrants the routine clinical assessment of endothelial function in HIV-positive patients to circumvent potential CVD events. Several different non-invasive strategies have been employed to assess endothelial function in clinical research studies yielding incon

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The Role of Inflammation in the Development of GDM and the Use of Markers of Inflammation in GDM Sc-borns are at risk of developing type 2 diabetes in the future. The screening and diagnostic criteria for GDM are inconsistent and thus novel biomarkers of GDM are required to strengthen the screening and diagnostic processes in GDM. Chronic low-grade inflammation is linked to the majority of the we

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ATAD3A on the Path to Cancer,ing mitochondrial dynamics, cell death and cholesterol metabolism. Overexpression and/or mutation of the ATAD3A gene have been observed in different types of cancer, associated with cancer development and progression. The dysregulated ATAD3A acts as a broker of a mitochondria-endoplasmic reticulum c