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Titlebook: Retinal and Choroidal Angiogenesis; J.S. Penn Book 2008 Springer Science+Business Media B.V. 2008 Choroidal.Penn.Retinal.angiogenesis.regu

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楼主: architect
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Neovascularization in Models of Branch Retinal Vein Occlusionponse shows high variability within and between species. However, animal models of ischemia-associated intraocular neovascularization from branch retinal vein occlusion have been employed with success to demonstrate therapeutic effects of pharmaceutical agents and to study mechanisms of angiogenesis
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Hypoxia and Retinal Neovascularizationon associated with blindness and vision loss in a variety of retinopathies. Review of the existing literature and results of new experiments from our laboratory strongly suggest that the oxygen-based pathophysiology stimulating retinal NV is more complicated than previously thought. Our evidence ide
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Hypoxia Inducible Factor-1 and VEGF Inductionncreased in response to hypoxia. This increase results from increased transcription as well as increased stabilization of the VEGF transcript. The increase in VEGF mRNA transcription is mediated by hypoxia inducible factor-1 (HIF-1), a heterodimeric transcription factor that is regulated by oxygen t
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Eph Receptor Tyrosine Kinases: Modulators of Angiogenesisvolved in angiogenesis, receptor tyrosine kinases (RTKs) have emerged as critical mediators of neovascularization. This review will focus on the youngest family of essential vascular RTKs, the Eph receptors, and ephrins, their corresponding ligands. We will summarize our current understanding of Eph
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The Regulation of Retinal Angiogenesis by Cyclooxygenase and the ProstanoidsAIDs has been associated with a reduced risk of colorectal cancer, which may be in part a consequence of reduced tumor-associated angiogenesis. These findings suggest that cyclooxygenase and the prostanoids may regulate angiogenesis. Several potentially blinding retinopathies have angiogenic compone
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