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Titlebook: Resistance to Targeted ABC Transporters in Cancer; Thomas Efferth Book 2015 Springer International Publishing Switzerland 2015 P-glycoprot

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发表于 2025-3-21 19:04:58 | 显示全部楼层 |阅读模式
书目名称Resistance to Targeted ABC Transporters in Cancer
编辑Thomas Efferth
视频video
概述Provides up-to-date research on the role of ABC transporters in drug-resistant tumors.Examines the potential of radiopharmaceuticals for diagnosis of multidrug-resistant tumors and of nanotechnology t
丛书名称Resistance to Targeted Anti-Cancer Therapeutics
图书封面Titlebook: Resistance to Targeted ABC Transporters in Cancer;  Thomas Efferth Book 2015 Springer International Publishing Switzerland 2015 P-glycoprot
描述This critical review volume explores the theme of ABC transporters in the context of basic cancer research and its role in drug-resistant tumors. The chapters provided complement basic research by including investigations from translational applications to clinical oncology. The development of resistance is a major obstacle in cancer chemotherapy and the field has been moving rapidly in terms of determining the mechanisms for blocking ABC transporter-mediated drug efflux by specific inhibitors and thereby overcoming multidrug resistance. The volume covers these issues in careful detail. Additional topics include the relevance of ABC transporters in resistance to novel and established anticancer drugs and prognosis of patients to compounds, compounds used in photodynamic therapy, tyrosine kinase inhibitors and others. Furthermore, the potential of radiopharmaceuticals for diagnosis of multidrug-resistant tumors and of nanotechnology to combat drug-resistant tumors is also discussed.
出版日期Book 2015
关键词P-glycoprotein; anticancer drugs; multidrug resistance; nanotechnology; antibacterial drug resistance
版次1
doihttps://doi.org/10.1007/978-3-319-09801-2
isbn_softcover978-3-319-37996-8
isbn_ebook978-3-319-09801-2Series ISSN 2196-5501 Series E-ISSN 2196-551X
issn_series 2196-5501
copyrightSpringer International Publishing Switzerland 2015
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