Titlebook: Resistance to Immunotherapeutic Antibodies in Cancer; Strategies to Overco Benjamin Bonavida Book 2013 Springer Science+Business Media New

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Resistance to Targeted Anti-Cancer Therapeuticshttp://image.papertrans.cn/r/image/828452.jpg

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https://doi.org/10.1007/978-1-4614-7654-2Rituximab; antibody-drug conjugates; cancer drug resistance; mABs; monoclonal antibody; antibodies

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978-1-4899-8732-7Springer Science+Business Media New York 2013

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Resistance to Immunotherapeutic Antibodies in Cancer978-1-4614-7654-2Series ISSN 2196-5501 Series E-ISSN 2196-551X

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2196-5501 etic mechanisms of resistance by various mAbs.Covers the pot​​​​The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encourag

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Resistance to Anticancer Antibodies: From Mechanisms to Solutions,f resistance to monoclonal antibody therapy. In this review, we discuss the available data for three of the best described antibodies, rituximab, trastuzumab and cetuximab. A variety of approaches and strategies has been suggested or are currently being tested to circumvent resistance to these antibodies.