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Titlebook: Resistance to Ibritumomab in Lymphoma; Makoto Hosono,Jean-François Chatal Book 2018 Springer International Publishing AG, part of Springer

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Resistance and Heterogeneity of Intratumoral Antibody Distribution,mphoma shows a remarkable diversity in phenotypic, genetic, and microenvironment intratumoral heterogeneities..Heterogeneity is one of the most clinically relevant and rapidly evolving fields of cancer research. Despite this growing excitement in the fundamental research, tumor heterogeneity has lit
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Prospects for Enhancing Efficacy of Radioimmunotherapy,y. Yet it still has limitations that prevent its large-scale clinical use. This chapter reviews recent developments to overcome these limitations including new antibody specificities, pretargeting methods, fractionated injections, and the use of alpha emitters. Immuno-PET is also likely to assist in
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