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Titlebook: Resistance of Cancer Cells to CTL-Mediated Immunotherapy; Benjamin Bonavida,Salem Chouaib Book 2015 Springer International Publishing Swit

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发表于 2025-3-21 16:37:49 | 显示全部楼层 |阅读模式
书目名称Resistance of Cancer Cells to CTL-Mediated Immunotherapy
编辑Benjamin Bonavida,Salem Chouaib
视频videohttp://file.papertrans.cn/829/828446/828446.mp4
概述Explores the inhibition of CTL-cytotoxic function by tumor-derived T-regulatory cells, along with the inhibition of cytotoxic function by tumor induction of hypoxia.Discusses the overexpression of tra
丛书名称Resistance to Targeted Anti-Cancer Therapeutics
图书封面Titlebook: Resistance of Cancer Cells to CTL-Mediated Immunotherapy; Benjamin Bonavida,Salem Chouaib Book 2015 Springer International Publishing Swit
描述This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.
出版日期Book 2015
关键词HDAC inhibitors; Proteasome inhibitors; apoptosis; cytotoxic t lymphocytes; drug-resistant cancer cells;
版次1
doihttps://doi.org/10.1007/978-3-319-17807-3
isbn_softcover978-3-319-38067-4
isbn_ebook978-3-319-17807-3Series ISSN 2196-5501 Series E-ISSN 2196-551X
issn_series 2196-5501
copyrightSpringer International Publishing Switzerland 2015
The information of publication is updating

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