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Titlebook: Research in Computational Molecular Biology; 27th Annual Internat Haixu Tang Conference proceedings 2023 The Editor(s) (if applicable) and

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Statistically Consistent Rooting of Species Trees Under the Multispecies Coalescent Model that has an additional step for determining the rooted shape of each quintet tree. We prove that QR-STAR is statistically consistent under the multispecies coalescent model, and our simulation study shows that QR-STAR matches or improves on the accuracy of QR. QR-STAR is available in open source fo
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Sequence to Graph Alignment Using Gap-Sensitive Co-linear Chainingty of gap cost functions. We demonstrate empirically the ability of our provably-good chaining implementation to align long reads more precisely in comparison to existing aligners. For mapping simulated long reads from human genome to a pangenome DAG of 95 human haplotypes, we achieve . precision wh
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Translation Rate Prediction and Regulatory Motif Discovery with Multi-task Learningprediction accuracy in all the benchmarked datasets generated by various experimental techniques. We show that features learnt in human samples are directly transferable to another dataset in yeast systems, demonstrating its robustness in identifying evolutionarily conserved sequence motifs. Further
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